Accession Number: P01237
Prolactin is a hormone that is produced and secreted by the pituitary gland. Prolactin acts in an endocrine, paracrine, and autocrine manner. The prolactin receptor (PRLR) is expressed on many cell types, including cells of the reproductive organs, central nervous system, and breast cancer. Prolactin signal transduction occurs via JAK kinase signaling pathways. The primary function of prolactin is to regulate lactation, but prolactin also plays functional roles in the immune system and during cell growth, apoptosis, and differentiation.
Product Specifications*Source: Genetically modified E.coli.
Predicted MW: Monomer, 22.7 kDa (198 aa)
AA Sequence: MLPVCSGGDC QTPLPELFDR VVMLSHYIHT LYTDMFIEFD KQYVQDREFI AKAINDCPTS SLATPEDKEQ AQKVPPEVLLNLILSLVHSW NDPLFQLITG LGGIHEAPDA IISRAKEIEE QNKRLLEGIE KIISQAYPEA KGNEIYLVWS QLPSLQGVDE ESKDLAFYNNIRCLRRDSHK VDNYLKFLRC QIVHKNNC
Formulation: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 20 mM sodium phosphate, pH 7.5
*Lot-specific values for the following specifications are supplied with each product on its corresponding COA. The values provided here are minimum expected values to pass internal requirements.
|Specification||Method of Determination||Acceptance Criteria|
|Purity||Reducing and Non-Reducing SDS PAGE||≥95%|
|Endotoxin||Kinetic LAL||≤1 EUs/µg|
|Biological Activity||No biological activity data is available at this time||No biological activity data is available at this time|
Country of Origin: USA Shipping: Room temperature
Product Reconstitution: Sterile water at 0.1 mg/mL
Instructions: Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.
12 months from date of receipt when stored at -20°C to-80°C as supplied.
1 month when stored at 4°C after reconstituting as directed.
3 months when stored at -20°C to -80°C after reconstituting as directed.
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