Rat GM-CSF

Rat GM-CSF

Part Number: 300-03

Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) is hematopoietic factor produced by entothelial cells, monocytes, fibroblasts and T cells in response to a number of inflammatory mediators. GM-CSF is able to stimulate the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells.‚ 

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Description

Alternate Names:  CSF-2, Pluripoietin-α, MGI1GM               Accession Number: P48750   
Description:  Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) is hematopoietic factor produced by entothelial cells, monocytes, fibroblasts and T cells in response to a number of inflammatory mediators. GM-CSF is able to stimulate the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells.  GM-CSF can also stimulate some functional activities in mature granulocytes and macrophages.  Human and mouse GM-CSF show no cross-reactivity. 
Source:  Genetically modified E.coli
Predicted MW:  Monomer, 14.7 kDa (128 aa)
AA Sequence:  MAPTRSPNPV TRPWKHVDAI KEALSLLNDM RALENEKNED VDIISNEFSI QRPTCVQTRL KLYKQGLRGN LTKLNGALTM IASHYQTNCP PTPETDCEIE VTTFEDFIKN LKGFLFDIPF DCWKPVQK
Formulation:  Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 20 mM sodium bicarbonate, pH 8.5

Product Specifications*
*Lot-specific values for the following specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements. 

Specification

Method of Determination

Acceptance Criteria

Purity

Reducing and Non-Reducing SDS PAGE

≥95%

Endotoxin

Kinetic LAL

≤1 EUs/µg

Biological Activity

FDC-P1 cell proliferation

≤20 pg/mL

Preparation and Storage
Country of Origin:  USA        Shipping:  Room temperature             

Storage Prior to Reconstitution:  -20ºC 
Product Reconstitution:  Sterile water at 0.1 mg/mL 
Instructions:  Centrifuge vial before opening.  Suspend the product by gently pipetting the above recommended solution down the sides of the vial.  DO NOT VORTEX.  Allow several minutes for complete reconstitution.   For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80 ºC and avoid repeat freeze thaws.   

Expiration Date                       

  • 12 months from date of receipt when stored at -20 to -80 ºC as supplied. 
  • 1 month when stored at 4 ºC after reconstituting as directed.
  • 3 months when stored at -20 to -80 ºC after reconstituting as directed.

To receive more information or for a bulk quote, email us at quotes@shenandoah-bt.com.

Part Number: Other Terms:

Additional information

Dimensions 1 × 1 × 1 cm
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Mg: 1 mg, Midgi: 500 ug, Mini: 5 ug, Std.: 20 ug, Value: 100 ug

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