Alternate Names: T cell growth factor, TCGF, Aldesleukin
Description: Interleukin 2 (IL-2) is an immunomodulatory cytokine that is produced by lymphocytes. IL-2 signals through the IL-2R receptor to induce activated T cell proliferation and promote T cell differentiation. IL-2 also stimulates the proliferation and differentiation of B cells, natural killer cells, monocytes, and macrophages.
Source: Genetically modified E.coli.
Predicted MW: Monomer, 15.3 kDa (with 135 amino acids)
AA Sequence: MAPTSSSTKN TKKQLEPLLL DLQLLLKEVK NYENADLSRM LTFKFYMPKQ ATELKHLQCL VEELKALEGV LNLGQSKNSD SANIKESMNN INVTVLELKG SETSFKCEYD DETVTAVEFL NKWITFCQSI YSTLT
Formulation: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, pH 7.5
*Lot-specific values for the following specifications are supplied with each production lot on its corresponding COA.
|Specification||Method of Determination||Acceptance Criteria|
|Purity||Reducing and Non-Reducing SDS-PAGE||≥ 95%|
|Endotoxin||Kinetic LAL (50% confidence)||≤ 1 EUs/µg|
|Biological Activity||CTLL-2 cell proliferation||ED50 ≤ 1 ng/mL|
Preparation and Storage
THIS PRODUCT IS FOR RESEARCH USE ONLY AND IS NOT FOR USE IN HUMANS!
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