Mouse MIP-3 beta / CCL19

Mouse MIP-3 beta / CCL19

Part Number: 200-44

Macrophage inflammatory protein-3 beta (MIP-3 Ž²), also called CCL19, is a chemokine that is expressed in the thymus, lymph nodes, and activated bone marrow stromal cells. ‚ MIP-3 Ž² signals through the G protein-coupled receptor CCR7 to regulate normal lymphocyte recirculation. ‚ MIP-3 Ž² also functions ‚ during T cell trafficking to the thymus, and in T cell and B cell homing to the lymph nodes and secondary lymphoid organs. ‚ 

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Description

Alternate Names:  CCL19, SCYA19, ELC, Exodus-3               Accession Number: Q548P0
Description:  Macrophage inflammatory protein-3 beta (MIP-3 β), also called CCL19, is a chemokine that is expressed in the thymus, lymph nodes, and activated bone marrow stromal cells.  MIP-3 β signals through the G protein-coupled receptor CCR7 to regulate normal lymphocyte recirculation.  MIP-3 β also functions  during T cell trafficking to the thymus, and in T cell and B cell homing to the lymph nodes and secondary lymphoid organs.  
Source:  Genetically modified E.coli.
Predicted MW: Monomer, 9.2 kDa (83 aa)
AA Sequence:  GANDAEDCCL SVTQRPIPGN IVKAFRYLLN EDGCRVPAVV FTTLRGYQLC APPDQPWVDR IIRRLKKSSA KNKGNSTRRS PVS
Formulation:  Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)

Product Specifications*
*Lot-specific values for the following specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements. 

Specification

Method of Determination

Acceptance Criteria

Purity

Reducing and Non-Reducing SDS PAGE

≥95%

Endotoxin

Kinetic LAL

≤1 EUs/µg

Biological Activity

No biological activity data is available at this time

No biological activity data is available at this time 

Preparation and Storage
Country of Origin:  USA        Shipping:  Room temperature             

Storage Prior to Reconstitution:  -20°C
Product Reconstitution:  Sterile water at 0.1 mg/mL
Instructions:  Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Expiration Date                      
12 months from date of receipt when stored at -20°C to-80°C as supplied.
1 month when stored at 4°C after reconstituting as directed.
3 months when stored at -20°C to -80°C after reconstituting as directed.

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Part Number: Other Terms:

Additional information

Dimensions 1 × 1 × 1 cm
Select size

Mg: 1, Midgi: 500 ug, Mini: 5 ug, Std.: 20 ug, Value: 100 ug

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