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Part Number: 200-81
Interleukin 36 gamma (IL-36 ‰£) is a member of the interleukin 1 (IL-1) cytokine family and protects against pathogens in the skin, lung, and stomach epithelial barriers. IL-36 ‰£ binds the interleukin-1 receptor accessory protein (IL-1RAcP) and the orphan IL-1R-related protein 2 (IL-1Rrp2) receptors to activate NF-kB and MAP kinase signaling pathways, resulting in the induced production of inflammatory cytokines and chemokines.
[bulk_variations include=”6237″]
$67.00 – $5,881.00
Alternate Names: IL-1F9, IL-1 epsilon Accession Number: Q8R460
Description: Interleukin 36 gamma (IL-36 £) is a member of the interleukin 1 (IL-1) cytokine family and protects against pathogens in the skin, lung, and stomach epithelial barriers. IL-36 £ binds the interleukin-1 receptor accessory protein (IL-1RAcP) and the orphan IL-1R-related protein 2 (IL-1Rrp2) receptors to activate NF-kB and MAP kinase signaling pathways, resulting in the induced production of inflammatory cytokines and chemokines.
Source: Genetically modified E.coli.
Predicted MW: Monomer, 17.5 kDa (153 aa)
AA Sequence: MGRETPDFGE VFDLDQQVWI FRNQALVTVP RSHRVTPVSV TILPCKYPES LEQDKGIAIY LGIQNPDKCL FCKEVNGHPT LLLKEEKILD LYHHPEPMKP FLFYHTRTGG TSTFESVAFP GHYIASSKTG NPIFLTSKKG EYYNINFNLD IKS
Formulation: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
Product Specifications*
*Lot-specific values for the following specifications are supplied with each product on its corresponding COA. The values provided here are minimum expected values to pass internal requirements.
|
Specification |
Method of Determination |
Acceptance Criteria |
|
Purity |
Reducing and Non-Reducing SDS PAGE |
≥95% |
|
Endotoxin |
Kinetic LAL |
≤1 EUs/µg |
|
Biological Activity |
No biological activity data is available at this time |
No biological activity data is available at this time |
Preparation and Storage
Country of Origin: USA Shipping: Room temperature
Expiration Date
12 months from date of receipt when stored at -20°C to -80°C as supplied.
1 month when stored at 4°C after reconstituting as directed.
3 months when stored at -20°C to -80°C after reconstituting as directed.
To receive more information or for a bulk quote, email us at quotes@shenandoah-bt.com.
Part Number: Other Terms:
| Dimensions | 1 × 1 × 1 cm |
|---|---|
| Select size | Animal-Free Mg: 1 mg, Animal-Free Midgi: 500 ug, Animal-Free Mini: 5 ug, Animal-Free Std: 20 ug, Animal-Free Value: 100 ug, Mg: 1 mg, Midgi: 500 ug, Mini: 5 ug, Std.: 20 ug, Value: 100 ug |
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