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Part Number: 200-36
Interleukin 33 (IL-33) is a member of the IL-1 cytokine family and is constitutively expressed in smooth muscle and airway epithelial cells. ‚ IL-33 signals through the interleukin 1 receptor-like 1 (IL-1R1) and interleukin-1 receptor accessory protein (IL1RAP) receptors to ativate NF-ŽºB and MAPK signaling pathways. ‚ IL-33 functions to induce type 2 cytokine production in polarized Type 2 helper T (Th2) cells.
[bulk_variations include=”5927″]
$67.00 – $5,881.00
Alternate Names: NP-HEV
Accession Number: Q8BVZ5
Description: Interleukin 33 (IL-33) is a member of the IL-1 cytokine family and is constitutively expressed in smooth muscle and airway epithelial cells. IL-33 signals through the interleukin 1 receptor-like 1 (IL-1R1) and interleukin-1 receptor accessory protein (IL1RAP) receptors to ativate NF-κB and MAPK signaling pathways. IL-33 functions to induce type 2 cytokine production in polarized Type 2 helper T (Th2) cells.
Source: Genetically modified E.coli.
Predicted MW: Monomer, 17.7 kDa (159 aa)
AA Sequence: MSIQGTSLLT QSPASLSTYN DQSVSFVLEN GCYVINVDDS GKDQEQDQVL LRYYESPCPA SQSGDGVDGK KLMVNMSPIK DTDIWLHAND KDYSVELQRG DVSPPEQAFF VLHKKSSDFV SFECKNLPGT YIGVKDNQLA LVEEKDESCN NIMFKLSKI
Formulation: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, pH 7.5
Product Specifications*
*Lot-specific values for the following specifications are supplied with each product on its corresponding COA. The values provided here are minimum expected values to pass internal requirements.
|
Specification |
Method of Determination |
Acceptance Criteria |
|
Purity |
Reducing and Non-Reducing SDS PAGE |
≥90% |
|
Endotoxin |
Kinetic LAL |
≤1 EUs/µg |
|
Biological Activity |
D10S cell proliferation |
≤2 ng/mL; ≥ 5.0 x 10^5 units/mg (typical ED50 is < 1 ng/mL) |
Preparation and Storage
Country of Origin: USA Shipping: Room temperature
Expiration Date
12 months from date of receipt when stored at -20°C to-80°C as supplied.
1 month when stored at 4°C after reconstituting as directed.
3 months when stored at -20°C to -80°C after reconstituting as directed.
Part Number: Other Terms:
| Dimensions | 1 × 1 × 1 cm |
|---|---|
| Select size | Animal-Free Mg: 1 mg, Animal-Free Midgi: 500 ug, Animal-Free Mini: 2 ug, Animal-Free Std.: 10 ug, Animal-Free Value: 100 ug, Mg: 1 mg, Midgi: 500 ug, Mini: 2 ug, Std.: 10 ug, Value: 100 ug |
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