Mouse IL-31

Mouse IL-31

Part Number: 200-71

Interleukin 31 (IL-31) is an immunoregulatory cytokine that is expressed by activated type 2 T helper (Th2) cells.‚IL-31 signals through a heterodimer receptor consisting of the IL-31 Receptor A (IL-31RA) and the oncostatin M receptor (OSMR), which are expressed on monocytes, epithelial cells, and keratinocytes.‚IL-31 promotes allergic reactions and inflammatory skin diseases.‚

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Description

Accession Number: Q6EAL8
Description:  Interleukin 31 (IL-31) is an immunoregulatory cytokine that is expressed by activated type 2 T helper (Th2) cells.  IL-31 signals through a heterodimer receptor consisting of the IL-31 Receptor A (IL-31RA) and the oncostatin M receptor (OSMR), which are expressed on monocytes, epithelial cells, and keratinocytes.  IL-31 promotes allergic reactions and inflammatory skin diseases.
Source:  Genetically modified E.coli cells.
Predicted MW:  Monomer, 15.8 kDa (with 141 amino acids)
AA Sequence:  SHTLPVRLLR PSDDVQKIVE ELQSLSKMLL KDVEEEKGVL VSQNYTLPCL SPDAQPPNNI HSPAIRAYLK TIRQLDNKSV IDEIIEHLDK LIFQDAPETN ISVPTDTHEC KRFILTISQQ FSECMDLALK SLTSGAQQAT T
Formulation:  Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 20 mM sodium phosphate, 50 mM sodium chloride, pH 7.5

Product Specifications*


*Lot-specific values for the following specifications are supplied with each production lot on its corresponding COA. 

Specification Method of Determination Acceptance Criteria
Purity Reducing and Non-Reducing SDS-PAGE ≥95%
Endotoxin Kinetic LAL (50% confidence) ≤1 EUs/µg
Biological Activity No biological activity data is available at this time No biological activity data is available at this time
Preparation and Storage

Country of Origin:  USA
Shipping: 
Room temperature
Storage Prior to Reconstitution:  -20°C
Product Reconstitution:  Sterile water at 0.1 mg/mL
Instructions:  Centrifuge vial before opening.  Suspend the product by gently pipetting the above recommended solution down the sides of the vial.  DO NOT VORTEX.  Allow several minutes for complete reconstitution.  For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C, and avoid repeat freeze thaws.
Expiration Date:                      

12 months from date of receipt when stored at -20°C to-80°C as supplied.

1 month when stored at 4°C after reconstituting as directed.

3 months when stored at -20°C to -80°C after reconstituting as directed.

THIS PRODUCT IS FOR RESEARCH USE ONLY AND IS NOT FOR USE IN HUMANS!           

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Part Number: Other Terms:

Additional information

Dimensions 1 × 1 × 1 cm
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Animal-Free Mg: 1 mg, Animal-Free Midgi: 500 ug, Animal-Free Mini: 2 ug, Animal-Free Std.: 10 ug, Animal-Free Value: 100 ug, Mg: 1 mg, Midgi: 500 ug, Mini: 2 ug, Std.: 10 ug, Value: 100 ug

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