Description
Alternate Names: IL-25 Accession Number: Q8VHC9
Description: Interleukin 17E (IL-17E), also known as IL-25, is a member of the IL-17 family of cytokines. IL-17E binds to the IL-17RB receptor to stimulate the secretion of the proinflammatory interleukin 8 (IL-8) chemokine and to induce the activation of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB).
Source: Genetically modified E.coli.
Predicted MW: Dimer, 17.6/35.2 kDa (154/308 aa)
AA Sequence: MVSLRIQEGC SHLPSCCPSK EQEPPEEWLK WSSASVSPPE PLSHTHHAES CRASKDGPLN SRAISPWSYE LDRDLNRVPQ DLYHARCLCP HCVSLQTGSH MDPLGNSVPL YHNQTVFYRR PCHGEEGTHR RYCLERRLYR VSLACVCVRP RVMA
Formulation: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
Product Specifications*
*Lot-specific values for the following specifications are supplied with each product on its corresponding COA. The values provided here are minimum expected values to pass internal requirements.
Specification |
Method of Determination |
Acceptance Criteria |
Purity |
Reducing and Non-Reducing SDS PAGE |
≥90% |
Endotoxin |
Kinetic LAL |
≤1 EUs/µg |
Biological Activity |
No biological activity data is available at this time |
No biological activity data is available at this time |
Preparation and Storage
Country of Origin: USA Shipping: Room temperature
Product Reconstitution: Sterile 10 mM HCl at 0.1 mg/mL
Instructions: Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.
Expiration Date
12 months from date of receipt when stored at -20°C to -80°C as supplied.
1 month when stored at 4°C after reconstituting as directed.
3 months when stored at -20°C to -80°C after reconstituting as directed.
Part Number: Other Terms:
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