Human/Mouse/Rat BMP-2

Human/Mouse/Rat BMP-2

Part Number: 800-02

Human BMP 2, Bone Morphogenetic Protein 2 recombinant protein is used in cell culture work related to bone & cartilage development. BMP2 is tested for biological activity via an Alkaline phosphatase activity in ATDC-5 cells. Lyophilized protein, high purity & low endotoxin. BMP manufacturing in the USA by BMP-2 Manufacturer Shenandoah.‚ 

[bulk_variations include=”4118″]

$67.00$4,657.00

Clear

Description

Catalog Numbers:  800-02 is a replacement for Human 100-53 / Mouse 200-79 / Rat 300-34 (100% sequence identity)

Description:  Bone morphogenetic protein 2 (BMP-2 or BMP2) is a member of the bone morphogenetic protein (BMP) family and functions as a potent inducer of bone and cartilage development. BMP proteins are synthesized as large precursor molecules which are cleaved by proteolytic enzymes. Bioactive BMP-2 consists of forming a homodimer or a heterodimer with a related BMP, such as BMP-7. BMP-2 signals through type I and type II receptor tyrosine kinases in conjuction with SMAD proteins to directly promote osteoblast differentiation. BMP-2 is also important during cardiac development and supports epicardial cell migration. 

Alternate Names:  BMP-2A               Accession Number: P12643

Source:  Genetically modified E.coli.
Predicted MW: Dimer, 13.0/26.1 kDa (115/230 aa)
AA Sequence:  MQAKHKQRKR LKSSCKRHPL YVDFSDVGWN DWIVAPPGYH AFYCHGECPF PLADHLNSTN HAIVQTLVNS VNSKIPKACC VPTELSAISM LYLDENEKVV LKNYQDMVVE GCGCR
Formulation:  Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)

Product Specifications*

*Lot-specific values for the following specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements. 

Specification

Method of Determination

Acceptance Criteria

Purity

Reducing and Non-Reducing SDS PAGE

≥95%

Endotoxin

Kinetic LAL

≤1 EUs/µg

Biological Activity

Alkaline phosphatase activity induced in ATDC-5 cells

≤250 ng/mL 

Preparation and Storage

Country of Origin:  USA       
Shipping:  Room temperature
Storage Prior to Reconstitution:  -20°C
Product Reconstitution:  Sterile water at 0.1 mg/mL

Instructions:  Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Expiration Date

  • 12 months from date of receipt when stored at -20°C to -80°C as supplied.
  • 1 month when stored at 4°C after reconstituting as directed.
  • 3 months when stored at -20°C to -80°C after reconstituting as directed.
 

To receive more information or for a bulk quote, email us at quotes@shenandoah-bt.com.

Part Number: Other Terms:

Additional information

Dimensions 1 × 1 × 1 cm
Select size

Animal-Free Mg: 1 mg, Animal-Free Midgi: 500 ug, Animal-Free Mini: 2 ug, Animal-Free Std.: 10 ug, Animal-Free Value: 100 ug, Mg: 1 mg, Midgi: 500 ug, Mini: 2 ug, Std.: 10 ug, Value: 100 ug

Reviews

There are no reviews yet.

Be the first to review “Human/Mouse/Rat BMP-2”

Your email address will not be published.