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Human / Mouse TGF-beta 3 (Liquid)

Human / Mouse TGF-beta 3 (Liquid)

Part Number: 800-07

Transforming growth factors (TGFs) are multifunctional peptides that regulate growth and differentiation in most cell types. The TGF-Ž² family of proteins signal through serine/threonine kinase receptors. TGF-Ž² isoforms (TGF-Ž²1, -Ž²2, and ¢‚¬€œŽ²3) have overlapping, yet distinct biological actions in developing and adult tissues.

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Description

Catalog Number: 800-07 is a replacement for human 100-109 / mouse 200-27 (100% sequence identity)

Accession Number: P10600
Description:  Transforming growth factors (TGFs) are multifunctional peptides that regulate growth and differentiation in most cell types. The TGF-β family of proteins signal through serine/threonine kinase receptors. TGF-β isoforms (TGF-β1, -β2, and –β3) have overlapping, yet distinct biological actions in developing and adult tissues. TGF-β3 is an important factor in regulating cell adhesion and accelerating wound repair. TGF-β3 also functions during osteoblast proliferation, chemotaxis, and collagen synthesis.
Source:  Genetically modified E.coli.
Predicted MW: Dimer, 12.9/25.7 kDa (113/226 aa)
AA Sequence:  MALDTNYCFR NLEENCCVRP LYIDFRQDLG WKWVHEPKGY YANFCSGPCP YLRSADTTHS TVLGLYNTLN PEASASPCCV PQDLEPLTIL YYVGRTPKVE QLSNMVVKSC KCS
Formulation:  In solution: 10 mM acetic acid and 20% Ethanol at a concentration of 0.25 mg/mL

Product Specifications*
*Lot-specific values for the following specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements. 

Specification

Method of Determination

Acceptance Criteria

Purity

Reducing and Non-Reducing SDS PAGE

≥95%

Endotoxin

Kinetic LAL

≤1 EUs/µg

Biological Activity

Inhibition of IL-4-induced HT-2 cell proliferation

≤1 ng/mL 

Preparation and Storage

Country of Origin:  USA        Shipping:  Ice pack             
Storage:  Centrifuge vial before opening. DO NOT VORTEX. Store at 4°C.

Expiration Date:                      
12 months from date of receipt when stored at 4°C as supplied.

To receive more information or for a bulk quote, email us at quotes@shenandoah-bt.com.

Part Number: Other Terms:

Additional information

Weight 1 g
Dimensions 1 × 1 × 1 cm
Select size

Animal-Free Mg: 1 mg, Animal-Free Midgi: 500 ug, Animal-Free Mini: 2 ug, Animal-Free Std.: 10 ug, Animal-Free Value: 100 ug, Mg: 1 mg, Midgi: 500 ug, Mini: 2 ug, Std.: 10 ug, Value: 100 ug

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