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Part Number: 800-07
Transforming growth factors (TGFs) are multifunctional peptides that regulate growth and differentiation in most cell types. The TGF-Ž² family of proteins signal through serine/threonine kinase receptors. TGF-Ž² isoforms (TGF-Ž²1, -Ž²2, and ¢‚¬€œŽ²3) have overlapping, yet distinct biological actions in developing and adult tissues.
[bulk_variations include=”4941″]
$67.00 – $5,881.00
Catalog Number: 800-07 is a replacement for human 100-109 / mouse 200-27 (100% sequence identity)
Accession Number: P10600
Description: Transforming growth factors (TGFs) are multifunctional peptides that regulate growth and differentiation in most cell types. The TGF-β family of proteins signal through serine/threonine kinase receptors. TGF-β isoforms (TGF-β1, -β2, and –β3) have overlapping, yet distinct biological actions in developing and adult tissues. TGF-β3 is an important factor in regulating cell adhesion and accelerating wound repair. TGF-β3 also functions during osteoblast proliferation, chemotaxis, and collagen synthesis.
Source: Genetically modified E.coli.
Predicted MW: Dimer, 12.9/25.7 kDa (113/226 aa)
AA Sequence: MALDTNYCFR NLEENCCVRP LYIDFRQDLG WKWVHEPKGY YANFCSGPCP YLRSADTTHS TVLGLYNTLN PEASASPCCV PQDLEPLTIL YYVGRTPKVE QLSNMVVKSC KCS
Formulation: In solution: 10 mM acetic acid and 20% Ethanol at a concentration of 0.25 mg/mL
Product Specifications*
*Lot-specific values for the following specifications are supplied with each product on its corresponding COA. The values provided here are minimum expected values to pass internal requirements.
|
Specification |
Method of Determination |
Acceptance Criteria |
|
Purity |
Reducing and Non-Reducing SDS PAGE |
≥95% |
|
Endotoxin |
Kinetic LAL |
≤1 EUs/µg |
|
Biological Activity |
Inhibition of IL-4-induced HT-2 cell proliferation |
≤1 ng/mL |
Preparation and Storage
Country of Origin: USA Shipping: Ice pack
Storage: Centrifuge vial before opening. DO NOT VORTEX. Store at 4°C.
Expiration Date:
12 months from date of receipt when stored at 4°C as supplied.
To receive more information or for a bulk quote, email us at quotes@shenandoah-bt.com.
Part Number: Other Terms:
| Weight | 1 g |
|---|---|
| Dimensions | 1 × 1 × 1 cm |
| Select size | Animal-Free Mg: 1 mg, Animal-Free Midgi: 500 ug, Animal-Free Mini: 2 ug, Animal-Free Std.: 10 ug, Animal-Free Value: 100 ug, Mg: 1 mg, Midgi: 500 ug, Mini: 2 ug, Std.: 10 ug, Value: 100 ug |
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