Alternate Names: CCL4, ACT-2 Accession Number: P13236
Description: Macrophage inflammatory protein-1 beta , also known as CCL4, is produced by macrophages and functions as a mitogen-inducible cytokine. MIP-1 signals through the chemokine receptor CCR5 to chemoattract immune cells. MIP-1 induces inflammatory responses, including neutrophil superoxide production. The MIP-1 and MIP-1 heterodimer exhibits antiviral activity against the human immunodeficiency virus 1 (HIV-1).
Source: Genetically modified E.coli.
Predicted MW: Monomer, 7.8 kDa (69 aa)
AA Sequence: APMGSDPPTA CCFSYTARKL PRNFVVDYYE TSSLCSQPAV VFQTKRGKQV CADPSESWVQ EYVYDLELN
Formulation: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
*Lot-specific values for the following specifications are supplied with each product on its corresponding COA. The values provided here are minimum expected values to pass internal requirements.
|Specification||Method of Determination||Acceptance Criteria|
|Purity||Reducing and Non-Reducing SDS PAGE||≥95%|
|Endotoxin||Kinetic LAL||≤1 EUs/µg|
|Biological Activity||No biological activity data is available at this time||No biological activity data is available at this time|
Preparation and Storage
Country of Origin: USA Shipping: Room temperature
Storage Prior to Reconstitution: -20°C
Product Reconstitution: Sterile water at 0.1 mg/mL
Instructions: Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.
12 months from date of receipt when stored at -20°C to -80°C as supplied.
1 month when stored at 4°C after reconstituting as directed.
3 months when stored at -20°C to -80°C after reconstituting as directed.
Complementary antibody products:
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Part Number: Other Terms: MIP1BETA, CCL4, BETA