Description

Alternate Names:  CCL4, ACT-2               Accession Number: P13236
Description:  Macrophage inflammatory protein-1 beta (MIP-1 β), also known as CCL4, is  produced by macrophages and functions as a mitogen-inducible cytokine.  MIP-1 β signals through the chemokine receptor CCR5 to chemoattract immune cells.  MIP-1 β induces inflammatory responses, including neutrophil superoxide production.  The MIP-1 β and MIP-1 α heterodimer exhibits antiviral activity against the human immunodeficiency virus 1 (HIV-1). 
Source:  Genetically modified E.coli.
Predicted MW: Monomer, 7.8 kDa (69 aa)
AA Sequence:  APMGSDPPTA CCFSYTARKL PRNFVVDYYE TSSLCSQPAV VFQTKRGKQV CADPSESWVQ EYVYDLELN
Formulation:  Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)

Product Specifications*
*Lot-specific values for the following specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements. 

Preparation and Storage
Country of Origin:  USA        Shipping:  Room temperature             

Storage Prior to Reconstitution:  -20°C
Product Reconstitution:  Sterile water at 0.1 mg/mL
Instructions:  Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Expiration Date:                      
12 months from date of receipt when stored at -20°C to -80°C as supplied.
1 month when stored at 4°C after reconstituting as directed.
3 months when stored at -20°C to -80°C after reconstituting as directed.

Complementary antibody products:
Need an Anti-Human MIP-1 beta antibody?  We recommend Anti-Human MIP-1beta Rabbit Polyclonal Antibody from ImmunoReagents.  If you are curious to know more about the relationship between Shenandoah and Immunoreagents, click here for the scoop.

To receive more information or a bulk quote, email us at quotes@shenandoah-bt.com.

Part Number: Other Terms: MIP1BETA, CCL4, BETA