Human IL-2

Human IL-2

Part Number: 100-12

Interleukin 2 (IL-2) is an immunomodulatory cytokine that is produced by lymphocytes.‚IL-2 signals through the IL-2R receptor to induce activated T cell proliferation and promote T cell differentiation. IL-2 also stimulates the proliferation and differentiation of B cells, natural killer cells, monocytes, and macrophages.

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Description

Alternate Names:T cell growth factor, TCGF, Aldesleukin

Accession Number: P60568

Description:Interleukin 2 (IL-2) is an immunomodulatory cytokine that is produced by lymphocytes.IL-2 signals through the IL-2R receptor to induce activated T cell proliferation and promote T cell differentiation. IL-2 also stimulates the proliferation and differentiation of B cells, natural killer cells, monocytes, and macrophages.

Source:Genetically modified E.coli.

Predicted MW: Monomer, 15.5 kDa (134 aa)

AA Sequence:MAPTSSSTKK TQLQLEHLLL DLQMILNGIN NYKNPKLTRM LTFKFYMPKK ATELKHLQCL EEELKPLEEV LNLAQSKNFH LRPRDLISNI NVIVLELKGS ETTFMCEYAD ETATIVEFLN RWITFCQSII STLT

Formulation:Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)

Product Specifications*

*Lot-specific values for the following specifications are supplied with each product on its corresponding COA.The values provided here are minimum expected values to pass internal requirements. 

Specification Method of Determination Acceptance Criteria
Purity Reducing and Non-Reducing SDS PAGE ‰¥95%
Endotoxin Kinetic LAL ‰¤1 EUs/µg
Biological Activity CTLL-2 cell proliferation  

‰¤3 ng/mL; ‰¥ 3.3 x 10^5 units/mg

 

**** International Units: The specific activity of Human IL-2 is approximately 1.8 x 10^4 IU/¼g, which is calibrated against recombinant human IL-2 WHO International Standard (NIBSC code: 86/500).

 Preparation and Storage

Country of Origin:USA      Shipping:Room temperature

Storage Prior to Reconstitution:-20°C

Product Reconstitution:Sterile 10 mM HCl at 0.1 mg/mL

Instructions:Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Expiration Date:

12 months from date of receipt when stored at -20°C to -80°C as supplied.

1 month when stored at 4°C after reconstituting as directed.

3 months when stored at -20°C to -80°C after reconstituting as directed.

Complementary antibody products:

Need an Anti-Human IL-2 antibody?We recommend Anti-Human IL-2 Rabbit Polyclonal Antibody from ImmunoReagents.If you are curious to know more about the relationship between Shenandoah and Immunoreagents, click here for the scoop.

To receive more information or a bulk quote, email us at quotes@shenandoah-bt.com.

Part Number: Other Terms: IL2

Additional information

Dimensions 1 × 1 × 1 cm
Select size

Animal-Free Mg: 1 mg, Animal-Free Midgi: 500 ug, Animal-Free Mini: 10 ug, Animal-Free Std.: 50 ug, Animal-Free Value: 100 ug, Mg: 1 mg, Midgi: 500 ug, Mini: 10 ug, Std.: 50 ug, Value: 100 ug

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