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Part Number: 100-195
Interleukin-1 receptor antagonist (IL-1RA) binds the interleukin 1 receptor (IL-1R) to antagonize interleukin 1 alpha and beta signaling.‚IL-1RA is secreted by immune cells, epithelial cells, hepatocytes, and adipocytes to inhibit IL-1-induced inflammation.‚IL-1RA therapy is used to treat auto-inflammatory diseases such as diabetes and rheumatoid arthritis.‚
[bulk_variations include=”6411″]
$67.00 – $1,226.00
Product Specifications*
*Lot-specific values for the following specifications are supplied with each production lot on its corresponding COA.
|
Specification |
Method of Determination |
Acceptance Criteria |
|
Purity |
Reducing and Non-Reducing SDS-PAGE |
≥ 95% |
|
Endotoxin |
Kinetic LAL (50% confidence) |
≤ 1 EUs/µg |
|
Biological Activity |
Inhibition of human IL-1 alpha induced proliferation of D10.G4.1 cells |
ED50 ≤ 50 ng/mL |
Preparation and Storage
Country of Origin: USA Shipping: Room temperature
Storage Prior to Reconstitution: -20°C
Product Reconstitution: Sterile water at 0.1 mg/mL
Instructions: Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.
Expiration Date:
12 months from date of receipt when stored at -20°C to-80°C as supplied.
1 month when stored at 4°C after reconstituting as directed.
3 months when stored at -20°C to -80°C after reconstituting as directed.
THIS PRODUCT IS FOR RESEARCH USE ONLY AND IS NOT FOR USE IN HUMANS!
To receive more information or a bulk quote, email us at quotes@shenandoah-bt.com.
Part Number: Other Terms:
| Dimensions | 1 × 1 × 1 cm |
|---|---|
| Select size | Animal-Free Mg: 1 mg, Animal-Free Midig: 500 ug, Animal-Free Mini: 20 ug, Animal-Free Std.: 100 ug, Animal-Free Value: 250 ug, Mg: 1 mg, Midig: 500 ug, Mini: 20 ug, Std.: 100 ug, Value: 250 ug |
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