Description
Description: Fibroblast growth factor 22 (FGF-22) is a mediator of synaptogenesis in the adult nervous system and functions to regulate synapse formation and maturation. FGF-22 is expressed in the inner hair cell and functions to maintain ribbon synapse number to protect functional hearing. In the hippocampus, FGF-22 promotes excitatory synapse formation through binding the FGFR2b and FGFR1b receptors. FGF-22 is also required for axonal circuit remodeling after spinal cord injury.
Source: Genetically modified E.coli.
Predicted MW: Monomer, 17.3 kDa (149 aa)
AA Sequence: MTPSASRGPR SYPHLEGDVR WRRLFSSTHF FLRVDPGGRV QGTRWRHGQD SILEIRSVHV GVVVIKAVSS GFYVAMNRRG RLYGSRLYTVDCRFRERIEE NGHNTYASQR WRRRGQPMFL ALDRRGGPRP GGRTRRYHLS AHFLPVLVS
Formulation: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
Product Specifications*
*Lot-specific values for the following specifications are supplied with each product on its corresponding COA. The values provided here are minimum expected values to pass internal requirements.
Specification |
Method of Determination |
Acceptance Criteria |
Purity |
Reducing and Non-Reducing SDS PAGE |
≥95% |
Endotoxin |
Kinetic LAL |
≤1 EUs/µg |
Biological Activity |
No biological activity data is available at this time |
No biological activity data is available at this time |
Country of Origin: USA Shipping: Room temperature
Product Reconstitution: Sterile water at 0.1 mg/mL
Instructions: Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.
Expiration Date
12 months from date of receipt when stored at -20°C to-80°C as supplied.
1 month when stored at 4°C after reconstituting as directed.
3 months when stored at -20°C to -80°C after reconstituting as directed.
To receive more information or for a bulk quote, email us at quotes@shenandoah-bt.com.
Part Number: Other Terms:
Reviews
There are no reviews yet.