Alternate Names:CCL26, MIP-4 alpha, TSC-1,Accession Number: Q9Y258
Description:Eotaxin-3, also known as CCL26, MIP-4-alpha, and TSC-1, is a chemokine that is made by vascular endothelial and lung epithelial cells following interleukin 4 (IL-4) or interleukin 13 (IL-13) stimulation. Eotaxin-3 signals through the G protein-coupled chemokine receptor CCR3 to recruit eosinophils and basophils to inflammatory sites.
Source:Genetically modified E.coli.
Predicted MW: Monomer, 8.4 kDa (71 aa)
AA Sequence:TRGSDISKTC CFQYSHKPLP WTWVRSYEFT SNSCSQRAVI FTTKRGKKVC THPRKKWVQK YISLLKTPKQ L
Formulation:Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
*Lot-specific values for the following specifications are supplied with each product on its corresponding COA.The values provided here are minimum expected values to pass internal requirements.
|Specification||Method of Determination||Acceptance Criteria|
|Purity||Reducing and Non-Reducing SDS PAGE||‰¥95%|
|Endotoxin||Kinetic LAL||‰¤1 EUs/µg|
|Biological Activity||No biological activity data is available at this time||No biological activity data is available at this time|
Product Reconstitution:Sterile water at 0.1 mg/mL
Instructions:Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.
12 months from date of receipt when stored at -20°C to-80°C as supplied.
1 month when stored at 4°C after reconstituting as directed.
3 months when stored at -20°C to -80°C after reconstituting as directed.
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Part Number: Other Terms: CCL-26