Description
Alternate Names: None Accession Number: P23560
Brain-derived neurotrophic factor (BDNF) is a nerve growth factor that binds two receptors, the low-affinity nerve growth factor receptor (LNGFR) and the tropomyosin receptor kinase B (TrkB), to support neuron growth and survival. BDNF expression in the hippocampus is essential for long-term memory storage and learning. Human, mouse, rat, and pig BDNF are cross-reactive.
Source: Genetically modified E.coli.
Predicted MW: Noncovalent Homodimer, 13.6/27.3 kDa (120/240 aa)
AA Sequence: MHSDPARRGE LSVCDSISEW VTAADKKTAV DMSGGTVTVL EKVPVSKGQL KQYFYETKCN PMGYTKEGCR GIDKRHWNSQ CRTTQSYVRA LTMDSKKRIG WRFIRIDTSC VCTLTIKRGR
Formulation: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
Product Specifications*
*Lot-specific values for the following specifications are supplied with each product on its corresponding COA. The values provided here are minimum expected values to pass internal requirements.
Specification | Method of Determination | Acceptance Criteria |
Purity | Reducing and Non-Reducing SDS PAGE | ≥95% |
Endotoxin | Kinetic LAL | ≤1 EUs/µg |
Biological Activity | C6 cell proliferation | ≤2 ug/mL; ≥ 5.0 x 102 units/mg |
Preparation and Storage
Expiration Date
- 12 months from date of receipt when stored at -20°C to-80°C as supplied.
- 1 month when stored at 4°C after reconstituting as directed.
- 3 months when stored at -20°C to -80°C after reconstituting as directed.
Complementary products:
Need an Anti-Human BDNF antibody? We recommend Anti-Human BDNF Rabbit Polyclonal Antibody from ImmunoReagents. If you are curious to know more about the relationship between Shenandoah and Immunoreagents, click here for the scoop.
To receive more information or for a bulk quote, email quotes@shenandoah-bt.com.
Part Number: Other Terms: BDNF
Reviews
There are no reviews yet.