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CTGrade rh IL-6

CTGrade rh IL-6

Part Number: 500-06

Containing no animal-derived materials, CTGrade rh IL-6 is produced in E. coli, is Beta Lactam-free, and manufactured by Shenandoah Biotechnology, Inc. in an ISO 9001:2015 certified facility that follows cGMP guidelines. CTGrade interleukins and growth factors are designed to support basic, translational, and clinical research, as well as commercial applications. *

$1,065.00$6,750.00

Description

Containing no animal-derived materials, CTGrade rh IL-6 is produced in E. coli, is Beta Lactam-free, and manufactured by Shenandoah Biotechnology, Inc. in an ISO 9001:2015 certified facility that follows cGMP guidelines. CTGrade interleukins and growth factors are designed to support basic, translational, and clinical research, as well as commercial applications.*

● Extremely low endotoxin levels
● High biological activity verified by relevant bioactivity assay
● Carrier-free protein
● Available quantities: 50 µg, 100 µg, and 1 mg; custom sizes and packaging available

Interleukin 6 (IL-6) is an important pro-inflammatory and anti-inflammatory cytokine expressed by T cells, macrophages and muscle cells. IL-6 signals through a receptor complex containing two receptors, IL-6RŽ± and gp130. IL-6 has an important function in promoting fever and can serve to stimulate an immune response to trauma. IL-6 is often used for growth of hybridoma cell lines.

Technical Specifications**
Alternate Names: Interleukin-6, 26 kDa protein, IFN-β2, B cell differentiation factor (BCDF), BSF-2, HPGF, HSF, MGI-2
Accession Number: P05231
AA Sequence: PVPPGEDSKD VAAPHRQPLT SSERIDKQIR YILDGISALR KETCNKSNMC ESSKEALAEN NLNLPKMAEK DGCFQSGFNE ETCLVKIITG LLEFEVYLEY LQNRFESSEE QARAVQMSTK VLIQFLQKKA KNLDAITTPD PTTNASLLTK LQAQNQWLQD MTTHLILRSF KEFLQSSLRA LRQM
Purity: ≥ 97% by SDS-PAGE
Predicted Molecular Mass: 9 kDa
Formulation: 10 mM Sodium Phosphate, pH 7.5
Product Reconstitution: Sterile water
Endotoxin level: ≤ 0.1 EU/ug
Activity: Determined by its ability to stimulate the proliferation of mouse B9 cells. The expected ED50 range is 0.001 – 0.020 ng/ml.
Host Cell DNA: ≤ 10 pg/mL
Host Cell Protein: ≤ 30 ng/mL
Sterility: No Growth
Country of Origin: USA

Storage: Store at -20°C in a non-defrosting freezer. Transportation temperature is 2-8°C.

Shelf Life: The lyophilized product is stable for 36 months from the date of manufacture; 12 months from date of receipt when stored at -20° C to -80° C as supplied, 1 month when stored at 4°C after reconstituting as directed, and 3 months when stored at -20°C to -80°C after reconstituted as directed. Avoid repeated freeze-thaw cycles.

*For research use or further manufacturing and in ex vivo cell therapy applications.
**Lot-specific values for the following specifications are supplied with each product on its corresponding COA. The values provided here are minimum expected values to pass internal requirements.

Additional information

Dimensions 1 × 1 × 1 cm
Select size

Mg: 1mg, Mini: 50 ug, Std: 100ug

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