CTG Human IL-21

CTG Human IL-21

Shenandoah Biotechnology, Inc., a worldwide supplier of high-quality recombinant proteins, is pleased to provide Cell Therapy Grade™(CTG™) recombinant Human Interleukin-21(hIL-21). Interleukin-21 is a common -chain cytokine regulating many cell types of the immune system. The IL-21 receptor (IL-21R) activates the JAK/STAT signaling pathway and is expressed on T, B, and natural killer (NK) cells. IL-21 plays an important role in the development of humoral immunity through its effects on B cell biology including differentiation, affinity maturation and memory responses. IL-21 regulates T cell responses including survival of CD8+ T cells and inhibition of Treg cells. IL-21 plays a pivotal role in Hodgkin’s lymphoma and suppresses Contact Hypersensitivity reactions. In adoptive cellular therapies i.e., CAR T cells, IL-21 promotes a less differentiated phenotype while promoting the effector functions of the engineered cells.
Shenandoah Biotechnology’s CTG™ Recombinant Human IL-21 is manufactured to the highest quality standard within the industry. Rigorous quality control procedures ensure lot-to-lot consistency providing reproducibility in downstream cell culture processes. The release of CTG™ hIL-21 and future releases in the CTG™ product line from Shenandoah Biotechnology will enhance the development of cell-based therapies within the biopharmaceutical industry.



Additional information

Dimensions 1 × 1 × 1 cm
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Mg: 1mg, Mini: 50 ug, Std: 100ug


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